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. Author manuscript; available in PMC: 2016 Jul 1.
Published in final edited form as: Free Radic Biol Med. 2015 Apr 4;84:196–205. doi: 10.1016/j.freeradbiomed.2015.03.036

Figure 7. Ad-SOCS-1-mediated protection in ALI may be due to suppression of ASK-1.

Figure 7

Male and female C57Bl/6 mice transfected with recombinant Ad-SOCS-1 and Ad-GFP were exposed to room air (Normoxia) or 100% O2 (Hyperoxia) at 72 h as described in Material and Methods. Western blot analysis of ASK-1 and caspase-3 (total and cleaved) from cell lysates was obtained from Ad-SOCS-1- or Ad-GFP-treated cells under hyperoxic or normoxic conditions. GAPDH was used as an internal control. Data is representative of at least 3 independent experiments.