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. Author manuscript; available in PMC: 2016 Jul 1.

Published in final edited form as: Ann Epidemiol. 2015 Jan 31;25(7):492–498. doi: 10.1016/j.annepidem.2015.01.010

Table 3.

Summary of statistically significant results of stepwise regression models

	Original cohort (PLT)		Offspring (PRPPC)		Third Generation (PLT)		Third Generation (MPV)
Variable	Partial R²	P-value	Partial R²	P-value	Partial R²	P-value	Partial R²	P-value
Gender (female)	0.041	<.0001	0.003	0.0041	0.050	<0.0001	0.015	<0.0001

Age, years	0.005	0.0249	0.008	<0.0001	0.005	0.0001	0.004	0.0006

Hypertension medication					0.002	0.0170

Cigarette smoking	0.018	<.0001	0.006	<0.0001	0.004	0.0003

Aspirin use			0.002	0.0378			0.002	0.0309

Diabetes medication			0.004	0.0005	0.003	0.0038

PE/DVT (prevalence)					0.002	0.0071

CVA (prevalence)	0.004	0.0350

DBP (mmHg)			0.003	0.0068	0.004	0.0003

LDL cholesterol (mg/dL)					0.016	<0.0001

Total cholesterol (mg/dL)	0.012	0.0005	0.017	<0.0001

MPV (fL)					0.158	<0.0001

PLT (×10³/uL)							0.158	<0.0001

BMI					0.011	<0.0001	0.005	0.0001

Full model R²	0.080		0.050		0.256		0.187