Table 1. Genes induced in CEFs, HD11 macrophages and chicken tissues after S. Enteritidis infection.
| Gene/Locus | Description | Chicken embryo fibroblast | HD11 macrophage | Tissue | ||||
|---|---|---|---|---|---|---|---|---|
| Microarray | qPCR | qPCR | qPCR | |||||
| SE 147 | SE 11 | SE 147 | SE 11 | SE 147 | SE 147 | SE 147 | ||
| 4 h | 4 h | 4 h | 4 h | 4 h | Caecum | Spleen | ||
| CSF3 | colony stimulating factor 3 (granulocyte) | 18.26 * | 12.99 | 18.47 | 13.53 | 16.70 | 81.85 | 24.22 |
| IL8L2 (EMF-1) | interleukin 8-like 2 | 16.84 | 10.49 | 16.36 | 12.67 | 16.71 | 3.45 | 0.71 |
| IL1β | interleukin 1, beta | 13.62 | 16.96 | 15.19 | 22.08 | 11.56 | 41.03 | 7.98 |
| IL8L1 (K60) | interleukin 8-like 1 | 11.70 | 7.65 | 14.10 | 9.16 | 6.92 | 2.19 | 0.63 |
| SCYA4 (MIP-1β) | C-C chemokine ligand 4 | 9.95 | 6.09 | 13.67 | 7.94 | 4.91 | 23.68 | 7.37 |
| CCL20 (MIP-3α) | C-C motif chemokine ligand 20 | 7.89 | 3.75 | 6.86 | 3.46 | 16.87 | 7.39 | 11.86 |
| CCL17 | C-C motif chemokine ligand 17 | 4.65 | 3.77 | 2.49 | 2.34 | 2.27 | 0.65 | 0.31 |
| K123 | K123 protein | 4.36 | 4.20 | 5.50 | 4.69 | 6.43 | 10.68 | 1.22 |
| NFκBIζ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 4.34 | 3.84 | 5.97 | 4.15 | 3.50 | 1.24 | 1.21 |
| IL6 | interleukin 6 (interferon, beta 2) | 3.70 | 3.57 | 6.19 | 6.17 | 454.54 | 137.01 | 18.75 |
| NFκBIα | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 3.21 | 4.19 | 4.00 | 5.71 | 2.85 | 3.07 | 1.07 |
| G0S2 | G0/G1 switch 2 | 3.13 | 3.52 | 17.47 | 24.83 | 2.41 | 9.18 | 0.93 |
| LOC422654 | similar to K60 protein (chemokine CXC ligand 1-like) | 6.91 | 6.08 | 8.38 | 8.24 | 0.79 | 3.11 | 0.24 |
| LOC101750351 | uncharacterized | 5.95 | 4.39 | 6.91 | 4.90 | 1.17 | 0.91 | 1.27 |
| ENO2 | enolase 2 (gamma, neuronal) | 5.42 | 7.44 | 2.91 | 2.40 | 0.41 | 3.64 | 4.72 |
| TNIP2 | TNFAIP3 interacting protein 2 | 3.73 | 4.96 | 3.98 | 4.52 | 1.38 | 3.53 | 1.20 |
| IRF1 | interferon regulatory factor 1 | 3.67 | 3.84 | 4.21 | 4.84 | 1.89 | 4.91 | 1.74 |
| BU460569 | uncharacterized | 3.59 | 4.36 | 3.34 | 2.87 | 1.13 | 1.46 | 0.85 |
| MOBKL2C | MOB1, Mps One Binder kinase activator-like 2C | 3.42 | 3.21 | 3.54 | 3.20 | 1.65 | 3.29 | 1.38 |
Values in the table represent fold inductions to appropriate non-infected control.
* Bold numbers represent fold inductions higher than twofold and significantly different from non-infected controls at p < 0.05.