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. 2015 Apr 30;473(7):2316–2326. doi: 10.1007/s11999-015-4324-8

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© The Author(s) 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 4A–F — Sequential MRI features of Patient 2 who had an osteochondral defect, indicated by the arrow, are shown (A) for bone before treatment, (B) at 6 months, and (C) at 6 years, and for (D) cartilage before treatment, (E) at 6 months, and (F) at 6 years. The sequential MR images showed that the osteochondral defect was filled with cartilaginous tissue at 6 months. The bone defect was filled with bony tissue, and the cartilage defect was incompletely filled with cartilaginous tissue at 6 years.