Skip to main content
. Author manuscript; available in PMC: 2015 Jun 6.
Published in final edited form as: J Bone Miner Res. 2014 Aug;29(8):1872–1885. doi: 10.1002/jbmr.2213

Figure 6. μCT images and quantification of bone microstructure of fusion masses formed by rhBMP-2 and Oxy133.

Figure 6

. Top panel: μCTs of two representative animals from the indicated groups are shown. Arrowheads signify lack of bone formation; arrows signify bone formation. Group I (Control); intertranverse process space with no bone formation. Group II (BMP2); bone mass bridging the intertransverse process space and bilateral fusion at L4–L5. Group III (Oxy133–20mg); bone mass bridging the intertransverse process space and bilateral fusion at L4–L5. Group IV (Oxy133–2mg); bone mass bridging the intertransverse process space and bilateral fusion at L4–L5 in animals that showed induction of fusion by Oxy133. Group V (Oxy133–0.2mg); arrow on the far right indicates a small amount of bone formation from the L5 transverse process. Bottom panel: Quantitative assessment of bone microstructure from μCT imaging.