Table 4. Risk of skeletal fluorosis associated with GSTP1 Rs1695 in subjects overall and stratified by ethnicity.
Case (n) | Control (n) | crude OR (95% CI) | adjusted OR (95% CI)* | |
---|---|---|---|---|
All subjects | ||||
AA | 226 | 681 | 1.0 (ref) | 1.0 (ref) |
AG+GG | 121 | 386 | 0.945 (0.733, 1.217) | 0.907 (0.693,1.066) |
Tibetan | ||||
AA | 91 | 117 | 1.0 (ref) | 1.0 (ref) |
AG+GG | 32 | 68 | 0.605 (0.366, 0.999) | 0.558 (0.326,0.955) |
Kazakh | ||||
AA | 52 | 106 | 1.0 (ref) | 1.0 (ref) |
AG+GG | 46 | 86 | 1.090 (0.669, 1.776) | 1.082 (0.659,1.776) |
Mongolian | ||||
AA | 36 | 137 | 1.0 (ref) | 1.0 (ref) |
AG+GG | 22 | 66 | 1.269 (0.692, 2.326) | 1.225 (0.657,2.283) |
Han | ||||
AA | 39 | 255 | 1.0 (ref) | 1.0 (ref) |
AG+GG | 18 | 113 | 1.042 (0.571, 1.899) | 1.116 (0.605,2.057) |
Russians | ||||
AA | 8 | 66 | 1.0 (ref) | 1.0 (ref) |
AG+GG | 3 | 53 | 0.467 (0.118,1.847) | 0.446 (0.108,1.843) |
* Adjusted for age, sex, ethnicity, and fluoride exposure.