Table 5. Main cardiovascular and FOT parameters at baseline (room air) and after methacholine (MCh).
| Control | Mch | Paired t-test | |
|---|---|---|---|
| Mean RR interval, ms | 814 (109) | 798 (125) | 0.189 |
| RR-SD, ms | 50 (28) | 39 (24) | 0.040 |
| RMSSD, ms | 47 (26) | 38 (20) | 0.069 |
| SBP, mm Hg | 133 (26) | 130 (19) | 0.709 |
| DBP, mm Hg | 75 (13) | 74 (15) | 0.892 |
| BRS, ms∙mmHg-1 | 12.2 (6.8) | 10.5 (7.8) | 0.184 |
| SaO2, % | 98 (1) | 94 (3) | 0.001 |
| TO2I, % | 65 (10) | 61 (11) | < 0.001 |
| R5, cm H2O∙s∙L-1 | 1.70 (0.55) | 4.57 (1.26) | < 0.001 |
| R19, cm H2O∙s∙L-1 | 1.87 (0.61) | 3.47 (0.93) | < 0.001 |
| VT, L | 0.93 (0.17) | 0.64 (0.14) | 0.001 |
| E, L∙min-1 | 9.98 (2.01) | 8.26 (2.51) | 0.090 |
| CO2-ET, mm Hg | 40.5 (4.02) | 34.46 (3.51) | < 0.001 |
RR interval: interval between two RR wave peaks; RR-SD: standard deviation of RR interval; SBP and DBP: systolic and diastolic pressures, respectively; SaO2: oxygen saturation; TO2I: Tissue Oxygen Index; R5 and R19, inspiratory resistance at 5 and 19 Hz, respectively; VT: tidal volume; E: minute ventilation; CO2-ET: carbon dioxide end-tidal. Data are mean ± SD.