Table 2. Cytotoxicity of the compounds isolated from EADs towards MCF-7 and MDA-MB-231 cells at 72 hours as reflected by IC50 value as determined by MTT assay.
Compounds | MCF-7 | MDA-MB-231 |
---|---|---|
IC50 (μg/mL) | IC50 (μg/mL) | |
1 | >100 | >100 |
2 | >100 | >100 |
3 | >100 | >100 |
4 | 36 ± 1.7 a | 35 ± 1.3 a |
5 | >100 | 83 ± 2.1 a |
6 | >100 | >100 |
Data are represented as IC50 ± SD of three replicates from three independent tests.
a indicates statistically significantly different from untreated control (P<0.05).