Fig 10. In vitro glucose assay in derived IPCs.

(A) Insulin secreted in cultured media in response to various concentrations of glucose from 5.5 to 25 mM; (B) C-peptide released in culture media; (C) Intracellular insulin content in each concentration of glucose that normalized with total cellular protein; (D) Intracellular C-peptide content in different concentrations of glucose that normalized with total cellular protein. Significant amounts of insulin and C-peptide were obtained in MSCs^{miR-375+anti-miR-9} group. The data are presented as mean ± SEM. P <0.05.