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. 2015 Jun 5;10(6):e0129365. doi: 10.1371/journal.pone.0129365

Fig 1. Coexpression of USP18 increases electrogenic peptide transport in PEPT1-expressing Xenopus laevis oocytes.

Fig 1

A: Representative original tracings showing Igly-gly in Xenopus laevis oocytes injected with water (a), expressing USP18 alone (b) or expressing PEPT1 without (c) or with additional coexpression of wild type USP18 (d). B: Arithmetic means ± SEM (n = 12–18) of Igly-gly in Xenopus laevis oocytes injected with water (striped bar), or expressing USP18 alone (grey bar) or expressing PEPT1 without (white bar) or with (black bar) USP18. C: Representative original tracings showing glycine-glycine (2 mM)—induced current (Igly-gly) in Xenopus laevis oocytes injected with (a) 10 ng, (b) 15ng, or (c) 20ng cRNA encoding PEPT1. D: Arithmetic means ± SEM (n = 9–10) of Igly-gly in Xenopus laevis oocytes injected with 10 ng (striped bar) or 15 ng (grey bar) or 20 ng (black bar) cRNA encoding PEPT1. *** (p<0.001) indicates statistically significant difference from the absence of USP18.