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. 2015 Jun 5;10(6):e0128878. doi: 10.1371/journal.pone.0128878

Table 2. Parameters used in the model and corresponding references.

Parameter Symbol Value Ref.
VEGF Diffusion Equation Parameters
VEGF Diffusion D 3.6 x 10 −4 cm2/h [73]
VEGF Decay λ 0.9375 h-1 [73]
VEGF Uptake β 0.06 pg/EC/hr [74]
VEGF Source S 0.035 pg/pixel [75]
Activation Threshold v a 0.0001 pg [1]
Cellular Pott’s Model Parameters
EC–EC Adhesion J ee 30 E/L [12]
EC–Fluid Adhesion J ef 76 E/L [12]
EC–Matrix Adhesion J em 66 E/L [12]
Fluid–Fluid Adhesion J ff 71 E/L [12]
Fluid–Matrix Adhesion J fm 85 E/L [12]
Matrix–Matrix Adhesion J mm 85 E/L [12]
EC Membrane Elasticity γ e 0.8 E/L4 [12]
M&P Cell Chemotactic Sensitivity χ MP -1.55x1.11x106 E/conc [12]
M Cell Chemotactic Sensitivity χ M -1.42x1.11x106 E/conc [12]
P Cell Chemotactic Sensitivity χ P -1.40x1.11x106 E/conc [12]
Intracellular Continuity α 300 E/L [12]
Boltzmann Temperature kT 2.5 E [12]
Attraction Coefficient ψ 1600 E/L2
Blood Flow Parameters
Blood Hematocrit H 0.45 [76]
Plasma Viscosity μplasma 0.0012 Pa.s [77]
Shear Stress Activation Threshold τthreshold 0.2 dyne/cm2 [67]