Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Jun 2;21(6):845–854. doi: 10.1016/j.cmet.2015.04.016

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2015 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

Improved Morphological Features of Cox15^sm/sm::Opa1^Tg Skeletal Muscle

(A) H&E staining of skeletal muscles from mice of the different genotypes. Scale bar 100 μm.

(B) Quantification of the number of centralized nuclei in the different genotypes. 600 fibers/sample were analyzed (n = 4/genotype). Solid blue: WT; blue outline: Opa1^tg; solid red: Cox15^sm/sm; red outline: Cox15^sm/sm::Opa1^tg. Statistical significance was calculated by unpaired, two-tail Student’s t test: ^∗∗∗p < 0.005. Error bars represent SEM.

(C) Cross-sectional area of muscle fibers of gastrocnemius. 600 fibers/sample were analyzed (n = 4/genotype). Solid blue: WT; blue outline: Opa1^tg; solid red: Cox15^sm/sm; red outline: Cox15^sm/sm::Opa1^Tg. Statistical significance was calculated by unpaired, two-tail Student’s t test: ^∗p < 0.05; ^∗∗p < 0.01; ^∗∗∗p < 0.005. Error bars represent SEM.