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. 2015 Jun 4;96(6):857–868. doi: 10.1016/j.ajhg.2015.04.012

Figure 2.

Figure 2

Boxplot of the Ratio of Naive-MVN eGene p Values to Permutation-Test eGene p Values

Using different sample sizes (n = 70, 110, 144, 220, and 300), we measured eGene p values of the two approaches with 1 M permutations and 1 M samplings on 100 probes and computed the ratio of eGene p values between the two methods. A distribution of the ratio on 100 probes is plotted. We excluded outliers with very significant p values to minimize sampling errors in our estimates. Blue shading denotes 90% accuracy.