Improved Ancestry Estimation for the AMD Targeted Sequencing Data
(A) Distribution of the sample-specific Procrustes similarity score t, which compares the coordinates of the reference individuals in a sample-specific PCA map (one for each AMD sample) to the corresponding coordinates in the reference ancestry map, for 3,068 European samples when using the original POPRES reference panel with K = K′ = 2 and using the imputed POPRES reference panel with K = 2 and K′ = 20.
(B) Increase of the sample-specific Procrustes similarity score for 3,068 European samples when comparing results using the imputed reference panel with K = 2 and K′ = 20 to the results using the original POPRES reference panel with K = K′ = 2.