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T cell responses in RR-EAE mice following hAEC administration. Mononuclear cells were isolated from the spleen of NOD/Lt mice at day 37. Proliferative response of splenocytes stimulated with rMOG (a) or anti-CD3/CD28 (g). b–f Cytokine secretion profile in supernatant from rMOG stimulated splenocyte cultures. h–l Cytokine secretion profile in supernatant from anti-CD3/CD28 stimulated splenocyte cultures (n = 6 performed in triplicate, *P < 0.05 compared to PBS)
