Table 3.
Associations of early HIV exposure with anthropometry and body composition – HUU children and all HEU children not confirmed HIV-positivea,b
Adjusted for age and sexc (coefficient, 95 % CI) | P | Fully adjustedd (coefficient, 95 % CI) | P | |
---|---|---|---|---|
Raw measures (n = 388) | ||||
Weight (kg) | −0.93 (−2.15, 0.29) | 0.13 | −0.03 (−1.20, 1.15) | 0.96 |
Height (cm) | −0.27 (−1.48, 0.94) | 0.66 | 0.46 (−0.74, 1.67) | 0.45 |
BMI (kg/m2) | −0.53 (−1.07, 0.01) | 0.055 | −0.19 (−0.71, 0.33) | 0.48 |
Waist circumference (cm) | −0.77 (−2.03, 0.49) | 0.23 | −0.10 (−1.36, 1.15) | 0.87 |
Hip circumference (cm) | −1.74 (−3.24, −0.24) | 0.023 | −0.56 (−1.98, 0.86) | 0.44 |
Thigh circumference (cm) | −0.95 (−1.94, 0.04) | 0.06 | −0.31 (−1.27, 0.66) | 0.53 |
MUAC (cm) | −0.63 (−1.23, −0.04) | 0.037 | −0.21 (−0.78, 0.37) | 0.48 |
Triceps skinfold (mm) | −0.57 (−1.35, 0.21) | 0.15 | −0.02 (−0.76, 0.73) | 0.97 |
Subscapular skinfold (mm) | −0.61 (−1.31, 0.10) | 0.09 | −0.15 (−0.83, 0.53) | 0.66 |
Z scores (n = 388) | ||||
Height-for-age | −0.03 (−0.24, 0.17) | 0.75 | 0.09 (−0.11, 0.30) | 0.38 |
BMI-for age | −0.18 (−0.44, 0.08) | 0.18 | −0.03 (−0.28, 0.22) | 0.81 |
Bioelectrical impedanceb (n = 373) | ||||
Total fat percent | −1.21 (−2.22, −0.21) | 0.018 | −0.64 (−1.62, 0.34) | 0.20 |
Trunk fat percent | −1.06 (−2.07, −0.05) | 0.039 | −0.56 (−1.56, 0.43) | 0.27 |
Leg fat percent | −1.29 (−2.31, −0.28) | 0.013 | −0.73 (−1.72, 0.26) | 0.15 |
Arm fat percent | −1.16 (−2.15, −0.18) | 0.021 | −0.68 (−1.65, 0.29) | 0.17 |
a BMI body mass index, CI confidence interval, MUAC mid-upper arm circumference, HEU HIV-exposed, uninfected, HUU HIV-unexposed, uninfected
bCoefficients are differences between HEU and HUU controls
cAdjusted for age and sex for raw measures and bioelectrical impedance but not for Z scores
dAdjusted for age, sex, mother’s marital status, mother’s education, father’s education, mother’s occupation, father’s occupation and asset index tertile; Z scores not adjusted for age and sex