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. 2015 Apr 27;6(2):144–154. doi: 10.1002/jcsm.12021

Table 2.

Association between self-reported physical dysfunction and each sarcopenia definitions

Difficulty for physical function
n (%)/Na Walking difficultiesb 95 (3.7)/2661 Climbing stairsc 1100 (40.9)/2688 Descending stairsd 1371 (51.2)/2677 Rising from a chaire 1061 (39.5)/2685 Moving difficultiesf (≥3 difficulties)g 1301 (48.5)/2680
Initial model AIC 792 2896 3156 3029 2879
AUC %g 68 79 76 77 81
Definition I (n = 283) Baumgartner 1998, sarcopenia defined by ASM/h2 <5.45 kg/m2 ORa 1.5 1.1 1.4 1.3 1.6
95% CI 0.8, 2.7 0.8–1.6 1.0, 1.8 0.9, 1.1 1.2, 2.2
AIC 793 2897 3153 3029 2871
AUC %g 68 80 76 77 81
Definition II (n = 541) Newman 2003, sarcopenia defined by linear regression ORa 1.6 1.3 1.5 1.4 1.5
95% CI 0.9, 2.6 1.0, 1.7 1.2, 1.9 1.1, 1.7 1.2, 1.9
AIC 792 2893 3148 3025 2862
AUC %g 67 80 76 77 81
Definition III (n = 511) Delmonico 2007, sarcopenia defined by ASM/h2 <5.67 kg/m2 ORa 1.8 1.3 1.4 1.3 1.5
95% CI 1.1, 2.9 1.0, 1.7 1.1, 1.7 1.0, 1.6 1.2, 1.9
AIC 787 2894 3151 3028 2870
AUC %g 68 80 76 77 81
Definition IV (n = 142) Cruz-Jentoft 2010, sarcopenia defined by ASM/h2 <5.45 kg/m2 + GS <0.8 m/s or lowest quartile HG ORa 1.7 1.5 2.2 1.4 2.1
95% CI 0.7, 3.7 1.0, 2.2 1.5, 3.2 1.0, 2.2 1.4, 3.2
AIC 793 2895 3142 3028 2867
AUC %g 67 80 76 77 81
Definition V (n = 89) Muscaretoli 2010, sarcopenia defined by ASM/h2 <5.45 kg/m2 + GS <0.8 m/s ORa 1.4 2.3 2.2 2.4 2.7
95% CI 0.5, 3.8 1.4, 3.9 1.3, 3.6 1.5, 3.9 1.6, 4.6
AIC 794 2887 3148 3018 2860
AUC %g 67 80 76 77 81
Definition VI (n = 390) Fielding and Morley 2011, sarcopenia defined by ASM/h2 <5.67 kg/m2 + GS <1 m/s ORa 2.0 1.6 1.6 1.4 1.6
95% CI 1.2, 3.3 1.2, 2.1 1.2, 2.0 1.1, 1.8 1.3, 2.1
AIC 787 2886 3145 3024 2867
AUC %g 68 80 76 77 81

AIC, Akaike information criteria; ASM, appendicular skeletal muscle mass; AUC, area under curve; CI, confidence interval; GS, gait speed in metre per second (m/s); h, height; HG, handgrip strength; ORa, adjusted odds ratio.

a

Number and percentage of patients reporting the specified physical difficulty/number of patients in each model.

b

Adjusted for age, hypertension, pain, visual impairment, and previous job.

c

Adjusted for age, obesity, peripheral vascular disease, cancer, depression, pain, visual impairment, physical activity, and cognitive status.

d

Adjusted for age, obesity, hypertension, cancer, depression, pain, visual impairment, coronary heart disease, and physical activity.

e

Adjusted for age, obesity, peripheral vascular disease, depression, pain, visual impairment, and physical activity.

f

Moving difficulties: walking, climbing stairs, rising from a chair or bed, picking an object from the floor, lifting heavy objects, and reaching an object.

g

Adjusted for age, obesity, cancer, depression, pain, visual impairment, coronary heart disease, physical activity, and cognitive status.

h

Optimist was corrected by bootstrap procedure.