Table 2.

Gene expression profiles

	Healthy controls	Pre-cachexia	Cachexia
PGC-1α (AU)	0.20 ± 0.19	0.13 ± 0.05	0.13 ± 0.06
TFAM (AU)	0.16 ± 0.04	0.14 ± 0.04	0.16 ± 0.04
CS (AU)	0.21 ± 0.10	0.15 ± 0.06	0.17 ± 0.05
HAD (AU)	0.19 ± 0.04	0.19 ± 0.04	0.21 ± 0.04
HKII (AU)	0.18 ± 0.12	0.12 ± 0.13	0.21 ± 0.27
PFK (AU)	0.19 ± 0.10	0.17 ± 0.09	0.18 ± 0.05
COX III (AU)	0.25 ± 0.08	0.19 ± 0.06*	0.15 ± 0.05*
COX IV (AU)	0.22 ± 0.07	0.18 ± 0.06*	0.17 ± 0.05*
MyHC I (AU)	0.20 ± 0.09	0.18 ± 0.09	0.17 ± 0.09
MyHC IIA (AU)	0.22 ± 0.10	0.24 ± 0.11	0.16 ± 0.05
MyHC IIx (AU)	0.15 ± 0.07	0.32 ± 0.25*	0.17 ± 0.11†

AU, arbitrary units; PGC-1α, peroxisome proliferator-activated receptor gamma co-activator 1-alpha; TFAM, mitochondrial transcription factor A; CS, citrate synthase; HAD, β-hydroxyacyl-CoA dehydrogenase; HKII, hexokinase II; PFK, phosphofructokinase; COX III, mitochondrial-encoded cytochrome c oxidase III; COX IV, cytochrome c oxidase subunit IV isoform 1; MyHC, myosin heavy chain.

^*Statistically significant difference compared with healthy controls (P < 0.05).

^†Statistically significant difference compared with pre-cachexia (P < 0.05).

Data represent mean ± standard deviation.