Table 1.
Wavelength | Damage Characterization | Proteins observed | References |
---|---|---|---|
337 nm | 8-oxodG, 6,4PPs, CPDs γH2AX positive |
FEN1, PARP-1, XRCC1 | (6) |
351 nm | γH2AX positive | FUS/TLS | (33) |
364 nm | γH2AX negative | BRCA1, HMGN1, Pol β, XRCC1 | (17, 18, 21, 26, 27, 37) |
365 nm (low power) | γH2AX negative | CAF1-p150, LIGIII, PCNA, PNKP, Pol β XRCC1 | (14, 19) |
365 nm (high power) | γH2AX positive 8-oxodG |
BRCA1, CAF1-p150, NBS1, NEIL1, NEIL2, NTH1, OGG1, PCNA, RAD52 | (19) |
365 nm with Psoralen | γH2AX positive | NEIL1 | (70) |
365 nm with Ro19-8022 | 8-oxodG | NEIL1, NEIL2, NTH1, OGG1, Pol β, XRCC1 | (19) |
405 nm | Low power, γH2AX negative 16-800 μW, 8-oxodG and γH2AX positive |
FEN1, PCNA, Pol β, PNKP, XRCC1 | (16, 43, 44) |
405 nm with BrdU or Hoechst | 8-oxodG, CPDs γH2AX positive |
LIGI, LIGIII, OGG1, PARP-1, PARG, XRCC1 | (12, 13, 15, 22-24, 41, 42) |
405 nm with Ro19-8022 | 8-oxodG Negative for 6,4PPs, and CPDs |
CSB, OGG1, XPC, XRCC1 | (32, 69) |
435 nm | γH2AX negative | XRCC1 | (45) |
488 nm | γH2AX positive Negative for 8-oxodG, 6,4PPs, and CPDs |
ATM, LIGIII, PCNA, RPA XRCC1 | (46) |
514 nm with EtBr | 8-oxodG γH2AX positive |
XRCC1, HP1, OGG1 | (50) |
559 nm with Killer Red | γH2AX positive 8-oxodG |
FEN1, HP1, MED1, NEIL1, NEIL2, NTH1, PARP-1, PCNA, XRCC1 | (20) |
750 nm with Hoechst | γH2AX positive Negative for 8-oxodG |
XRCC1, OGG1, PARP-1, LIGIII, PNKP | (12) |
768 nm | None reported | OGG1 | (25) |
800 nm | None reported | FEN1, PCNA | (61) |