Table 2.
Risk of Incident HF, by LVH and initial biomarker level
| Hazard Ratios (95% CI) | |||
|---|---|---|---|
| LVH by echo |
Tertile of NT-proBNP |
Unadjusted | Risk-factor adjusted* |
| None | 1 | 1.0 | 1.0 |
| 2 | 1.22 (0.96, 1.50) | 1.22 (0.97, 1.52) | |
| 3 | 2.03 (1.64, 2.50) | 1.94 (1.56, 2.41) | |
| Yes | 1 | 1.87 (1.20, 2.91) | 1.71 (1.10, 2.67) |
| 2 | 2.52 (1.69, 3.76) | 2.07 (1.38, 3.10) | |
| 3 | 4.42 (3.28, 5.94) | 3.78 (2.78, 5.15) | |
| LVH by echo |
Tertile of hs cTnT |
Unadjusted | Risk-factor adjusted* |
| None | 1 | 1.0 | 1.0 |
| 2 | 1.69 (1.36, 210) | 1.36 (1.09, 1.69) | |
| 3 | 2.75 (2.23, 3.38) | 2.07 (1.67, 2.56) | |
| Yes | 1 | 2.62 (1.80, 3.81) | 2.31 (1.58, 3.36) |
| 2 | 2.20 (1.41, 3.44) | 1.70 (1.08, 2.66) | |
| 3 | 5.88 (4.37, 7.90) | 3.86 (2.84, 5.26) | |
Risk-Factor Adjusted: Age, race, gender, smoking, hypertension, diabetes, coronary heart disease, body mass index, eGFR<60 cc/min/1.73m2, LVEF<45%, and relative wall thickness (RWT).
Interaction of LVH with: NTproBNP: p=0.5; hs cTnT: p=0.6