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. Author manuscript; available in PMC: 2016 Jun 1.
Published in final edited form as: JACC Heart Fail. 2015 May 14;3(6):445–455. doi: 10.1016/j.jchf.2014.12.018

Table 2.

Risk of Incident HF, by LVH and initial biomarker level

Hazard Ratios (95% CI)
LVH by echo Tertile of
NT-proBNP
Unadjusted Risk-factor adjusted*
None 1 1.0 1.0
2 1.22 (0.96, 1.50) 1.22 (0.97, 1.52)
3 2.03 (1.64, 2.50) 1.94 (1.56, 2.41)
Yes 1 1.87 (1.20, 2.91) 1.71 (1.10, 2.67)
2 2.52 (1.69, 3.76) 2.07 (1.38, 3.10)
3 4.42 (3.28, 5.94) 3.78 (2.78, 5.15)
LVH by echo Tertile of hs
cTnT
Unadjusted Risk-factor adjusted*
None 1 1.0 1.0
2 1.69 (1.36, 210) 1.36 (1.09, 1.69)
3 2.75 (2.23, 3.38) 2.07 (1.67, 2.56)
Yes 1 2.62 (1.80, 3.81) 2.31 (1.58, 3.36)
2 2.20 (1.41, 3.44) 1.70 (1.08, 2.66)
3 5.88 (4.37, 7.90) 3.86 (2.84, 5.26)
*

Risk-Factor Adjusted: Age, race, gender, smoking, hypertension, diabetes, coronary heart disease, body mass index, eGFR<60 cc/min/1.73m2, LVEF<45%, and relative wall thickness (RWT).

Interaction of LVH with: NTproBNP: p=0.5; hs cTnT: p=0.6