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. Author manuscript; available in PMC: 2016 Jun 1.
Published in final edited form as: JACC Heart Fail. 2015 May 14;3(6):445–455. doi: 10.1016/j.jchf.2014.12.018

Table 3.

Risk of Heart failure with reduced EF, by LVH and initial biomarker level

Hazard Ratios (95% CI)
LVH by echo Tertile of
NT-proBNP 		Unadjusted Risk-factor
adjusted*
None 1 1.0 1.0
2 1.03 (0.64, 1.65) 1.00 (0.62, 1.62)
3 1.74 (1.11, 2.21) 1.66 (1.05, 2.62)
Yes 1 1.03 (0.64, 1.65) 0.93 (0.28, 3.04)
2 3.49 (1.72, 70.6) 2.92 (1.42, 5.99)
3 6.48 (3.82, 10.97) 5.06 (2.89, 8.86)
LVH by echo Tertile of hs
cTnT 		Unadjusted Risk-factor
adjusted*
None 1 1.0 1.0
2 2.30 (1.42, 3.73) 1.77 (1.08, 2.89)
3 3.64 (2.29, 5.80) 2.62 (1.62, 4.21)
Yes 1 2.70 (1.12, 6.51) 2.19 (0.90, 5.32)
2 3.38 (1.40, 8.14) 2.65 (1.10, 6.46)
3 12.94 (7.5, 22.23) 7.83 (4.43, 13.83)
*

Risk-Factor Adjusted: Adjustment covariates same as for Table 2.

Interaction of LVH with: NT-proBNP tertiles: p=0.07; hs-cTnT tertiles: p=0.4