Table 3.

Relationship between Human Milk and Necrotizing Enterocolitis: Results from Binary Logistic Regression Model

Variable	Coefficient	Odds Ratio (95% CI)	p-value
Any formula by DOL 14	1.245	3.47 (1.22 – 9.92)	0.020
Any human milk fortifier by DOL 14	0.565	1.76 (0.59 – 5.26)	0.311
Birth weight	−0.071	0.93 (0.74 – 1.18)	0.550
Small for gestational age	−0.431	0.65 (0.17 – 2.44)	0.523
Days to full feed	0.091	1.10 (1.02 – 1.18)	0.015
Birth weight *days to full feed interaction (centered)	0.0005	--	0.001
c-statistic		0.855

Notes: For infants with NEC and days to full feed that exceeded day of onset of NEC, days to full feed set equal to day of onset of NEC (N = 5) less (day of life of full feed – days to full feed). Model controls for race/ethnicity, gender and QI phase.