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. Author manuscript; available in PMC: 2016 Mar 21.
Published in final edited form as: Neonatology. 2015 Mar 21;107(4):304–311. doi: 10.1159/000371835

Figure 3. CXCR4 Blockade Improves Alveolarization in Hyperoxia-induced Lung injury (HILI).

Figure 3

A. H&E stained lung sections demonstrating improved alveolar structure in hyperoxia exposed rats treated with AMD3100. Original magnification x 100, scale bars: 100 μm.

B. Decreased mean linear intercept (MLI) observed in hyperoxia-AMD3100 treated animals (*p<0.05; RA-PL vs. hyperoxia-PL; **p<0.007, hyperoxia-PL vs. hyperoxia-AMD3100; n=10/group). White bars represent RA animals and black bars represent hyperoxia animals.

C. Increased septal density in hyperoxic-AMD3100 treated rats (*p<0.0001; RA-PL vs. hyperoxia-PL; **p<0.002, hyperoxia-PL vs. hyperoxia-AMD3100; n=10/group).