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Sequence alignment of IGFBP-6 from rat, mouse, human, cow, pig and zebrafish (2 gene products). Small residues are shown in red, acidic residues in blue, basic residues in magenta, and others in green. * fully conserved residue; : strongly conserved residue with similar properties; . weakly conserved residue. Alignment was performed using Clustal Omega v 1.2.1, EMBL-EBI (www.ebi.ac.uk) (Sievers, et al. 2011)
