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. 2015 Feb 10;20:119. doi: 10.11604/pamj.2015.20.119.5263

Table 2.

Accuracy of rapid immunochromatographic assays against ELISA stratified by testing facility

Parameter Specificity Sensitivity J-Index PPV NPV LR+ LR- RR
Hepatitis B virus
Total 97.8 97.0 1.0 84.2 99.6 43.2 0.0 8.11 (0.01-16.65)
Agogo 97.7 100 1.0 87.5 100 43.0 0.0 0.00 (0.00-40.44)
Bekwai 95.6 100 1.0 71.4 100 22.5 0.0 0.00 (0.00-48.91)
KATH 96.4 93.8 0.9 83.3 98.8 26.3 0.1 15.0 (0.01-30.31)
KNUST 100 100 1.0 100 100 NA 0.0 0.00 (0.00-83.25)
Sunyani 100 100 1.0 100 100 NA 0.0 0.00 (0.00-54.59)
Hepatitis C Virus
Total 97.2 25.0 0.2 27.3 96.9 9.0 0.8 68.75 (46.15-91.73)
Agogo 91.3 25.0 0.2 20.0 93.3 2.9 0.8 62.50 (28.91-96.59)
Bekwai 91.3 0.0 -0.1 0.0 91.3 0.0 1.1 75.00 (45.41-100)
KATH 100 50.0 0.5 100 98.0 NA 0.5 50.00 (15.00-85.00)
KNUST 100 NA NA NA 100 NA 1.0 NA
Sunyani 100 NA NA NA 100 NA 1.0 NA
Human Immuno virus
Total 88.9 100 0.9 8.3 100 9.0 0.0 0.00 (0.00-61.75)
Agogo 79.6 100 0.8 9.1 100 4.9 0.0 0.00 (0.00-83.25)
Bekwai 72.0 NA -0.5 0.0 100 0.0 1.4 NA
KATH 93.9 100 0.9 14.3 100 16.5 0.0 0.00 (0.00-83.25)
KNUST 100 NA NA NA 100 NA 1.0 NA
Sunyani 93.9 100 0.9 25.0 100 16.3 0.0 0.00 (0.00-83.25)

Data are presented as number. ELISA = enzyme immunosoebent assay; J-Index = Youden's statistic Index; LR+ = likelihood ratio positive; LR- = likelihood ratio negative; RR = residual risk; KATH = Komfo Anokye Teaching Hospital; KNUST = Kwame Nkrumah University of Science and Technology; NA = could not be calculated.