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| Response | Modified Hyper-CVAD, n = 68, % | Hyper-CVAD, n = 208, % | P |
|---|---|---|---|
| CR | |||
| Overall | 93 | 95 | NS |
| After course 1 | 78 | 77 | |
| CR with incomplete platelet recovery | 1 | 0 | |
| Partial response | 4 | 0 | NS |
| Resistant disease | 0 | 2 | NS |
| Induction mortality | 1 | 3 | NS |
Hyper-CVAD indicates fractionated cyclophosphamide, vincristine, doxoru-bicin, and dexamethasone; CR, complete response; NS, not significant.
