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. Author manuscript; available in PMC: 2016 Jul 10.
Published in final edited form as: J Control Release. 2015 Apr 30;209:280–287. doi: 10.1016/j.jconrel.2015.04.040

Figure 5. Pharmacokinetic analysis of TFV in mouse colorectal tissue.

Figure 5

The calculated amount of TFV present in mouse colorectal tissues is shown for up to 4 h after administration. 1% TFV was administered in the simulated colon solution (SCS) (150 mOsm), isotonic TBS (450 mOsm), 5% glycerol gel (760 mOsm), and Fleet® enema (2200 mOsm). Studies were performed in n ≥ 5 mice with highest and lowest value excluded to yield a total of n ≥ 3 sample points. Data is shown as mean ± SEM. *P < 0.05 using Student's t-test.