Skip to main content
. Author manuscript; available in PMC: 2016 Jul 1.
Published in final edited form as: Transl Res. 2015 Jan 13;166(1):12–27. doi: 10.1016/j.trsl.2015.01.004

Figure 2. Ischemia Reperfusion Injury and Recovery.

Figure 2

Intestinal ischemic injury occurs when the blood supply to a segment of intestine is compromised. Paradoxically, tissue damage may continue when blood flow is reestablished, a process call reperfusion injury. Following the initial injury induced by ischemia and reperfusion there are three important stages of intestinal epithelial repair. There is an immediate post injury or acute repair, a subsequent sub-acute period when cell proliferation occurs and a final, chronic stage of mucosal repair when normal architecture is re-established. ROM = Reactive Oxygen Metabolites