Table 2.
Association between cord blood PAH-DNA adducts on IQ at age 7, stratified by prenatal and recurrent material hardship (N=276)a
| Low Prenatal Material Hardship (N=158) | High Prenatal Material Hardship (N=118) | Interaction | Non-Recurrent Material Hardship (N=166) | Recurrent Material Hardship (N=110) | Interaction | |
|---|---|---|---|---|---|---|
| WISC components | βadducts (95% CI) | βadducts (95% CI) | βinteraction (95% CI) | βadducts (95% CI) | βadducts (95% CI) | βinteraction (95% CI) |
| Full Scale | −1.79 (−5.50, 1.93) | −5.81 (−10.35, −1.26)* | −4.66 (−10.43, 1.11) | −1.32 (−4.97, 2.33) | −6.63 (−11.28, −1.98)* | −5.59 (−11.37, 0.20) |
| Verbal Comprehension | −1.08 (−4.29, 2.14) | −3.36 (−7.61, 0.90) | −2.39 (−7.57, 2.80) | −0.79 (−3.98, 2.40) | −4.21 (−8.51, 0.09) | −3.13 (−8.32, 2.07) |
| Processing Speed | −3.59 (−8.21, 1.02) | −4.17 (−9.75, 1.41) | −0.97 (−8.09, 6.16) | −3.46 (−7.71, 0.79) | −4.02 (−10.13, 2.09) | −0.83 (−7.97, 6.30) |
| Perceptual Reasoning | −1.45 (−5.86, 2.95) | −5.44 (−10.27, −0.61)* | −4.66 (−11.20, 1.89) | −1.29 (−5.55, 2.96) | −5.66 (−10.71, −0.61)* | −4.74 (−11.32, 1.85) |
| Working Memory | 0.57 (−3.70, 4.85) | −6.67 (−11.38, −1.95)* | −8.07 (−14.48, −1.66)* | 1.24 (−3.13, 5.60) | −8.06 (−12.49, −3.63)* | −9.82 (−16.22, −3.42)* |
*
p-value<0.05
a
Adjusting for ETS, sex, maternal education, maternal intelligence, ethnicity, and the home caretaking environment.