Figure 2. DTI measures by diagnostic group.
Mean measures of fractional anisotropy (FA) and radial diffusivity (RD) with standard deviations. After controlling for controlling for age, race, sex, and hemisphere, the presented tracts exhibited a significant difference between groups in either RD or FA at unadjusted p-values (Supplemental Table 2). Statistical data show F values for group variable and the FDR-corrected p-value, with 2 degrees of freedom for the variable and 158 for the model. Overall, suicidal depressed subjects tended to have higher RD and lower FA in these tracts. Statistically significant group comparisons for regions surviving FDR correction are shown with brackets, ◆ p < 0.05, * p < 0.01.
CB/cg – cingulum, cingulate gyrus; CB/hpc – cingulum, hippocampus region; CR/super – superior corona radiata; CR/post – posterior corona radiata; CC, splen – splenium of the corpus callosum; ALIC – anterior limb of the internal capsule; PLIC – posterior limb of the internal capsule; ATR – anterior thalamic radiation; PTR – posterior thalamic radiation.