Table 2.
Comparison | DTI Measure | Cluster Maxima | MNI coordinates | Size | p value |
---|---|---|---|---|---|
Control > Depressed/Suicidal | FA | Corpus Callosum, Splenium | −10, 33, 24 | 6,529 | 0.020 |
FA | R. Corticospinal Tract | 23, −20, 59 | 503 | 0.046 | |
FA | R. Anterior Thalamic Radiation | 9, −4, 11 | 365 | 0.046 | |
RD | L. Superior Longitudinal Fasciculus | −18, −6, 7 | 11,495 | 0.021 | |
Depressed/Nonsuicidal > Depressed/Suicidal | FA | L. Post Corona Radiata | −26, −38, 23 | 17,533 | 0.010 |
RD | R. Anterior Thalamic Radiation | 7, −5, −1 | 25,846 | 0.004 |
All clusters showed a reduced fractional anisotropy (FA) and elevated radial diffusivity (RD) in the suicidal group compared with other groups. Cluster size measured in voxels.
Abbreviations: MNI = Montreal Neurological Institute