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. Author manuscript; available in PMC: 2016 Jun 1.
Published in final edited form as: J Mol Neurosci. 2015 Apr 23;56(2):377–387. doi: 10.1007/s12031-015-0556-z

Figure 1.

Figure 1

Vasoactive Intestinal Peptide deficient mice (VIP−/−) showed a lower body weight, fat mass and an increased lean mass. (A) VIP−/− mice had a consistently lower body weight average compared to WT mice throughout the 21.5 weeks of the study. (B) VIP−/− mice consistently demonstrated a lower tendency to accumulate body fat mass compared to WT mice beginning at 10.5 weeks of age through end of the study at 21.5 weeks of age. (C) VIP−/− mice showed a significant tendency as they aged to maintain their body lean mass compared to WT mice, as assessed at 10.5 weeks of age through the end of the study at 21.5 weeks of age. (D) VIP−/− mice had a significantly lower epididymal fat depot weight compared to WT mice.