Table 2.
Predictor variable | Pre-term N (%) | Term N (%) | Unadjusted OR | p | Adjusted OR | p |
---|---|---|---|---|---|---|
Total | 71 (13.5) | 454 (86.5) | ||||
Year of delivery | ||||||
1988–1996 | 17 (16.8) | 84 (83.2) | 1.05 (0.48–1.48) | 0.9 | ||
1997–2006 | 34 (11.6) | 259 (88.4) | 0.73 (0.38–1.38) | 0.33 | ||
2007–2011 | 20 (15.3) | 111 (84.7) | 1 | |||
Age (years) | ||||||
> 35 | 15 (11.8) | 112 (88.2) | 0.91 (0.35–1.63) | 0.84 | 0.71 (0.27–1.87) | 0.49 |
25–35 | 47 (14.2) | 285 (85.8) | 1.09 (0.48–1.52) | 0.82 | 0.98 (0.45–2.15) | 0.97 |
< 25 | 9 (13.8) | 56 (86.2) | 1 | 1 | ||
ART treatment | ||||||
No treatment | 13 (25.0) | 39 (75.0) | 2.70 (1.20–6.09) | 0.017 | 1.50 (0.33–6.78) | 0.60 |
NRTI/NNRTI | 14 (8.8) | 145 (91.2) | 0.81 (0.40–1.66) | 0.56 | 0.67 (0.27–1.63) | 0.37 |
Boosted | 23 (19.3) | 96 (80.7) | 2.01 (1.02–3.97) | 0.045 | 2.17 (1.05–4.51) | 0.038 |
Unboosted | 21 (10.8) | 174 (89.2) | 1 | 1 | ||
NRTI backbone | ||||||
None | 13 (25.5) | 38 (74.5) | 2.59 (1.04–6.42) | 0.041 | 1.40 (0.26–7.59) | 0.69 |
AZT/3TC | 37 (11.5) | 285 (88.5) | 1.12a (0.53–2.35) | 0.44 | 0.50 (0.18–1.36) | 0.17 |
Tdf/3TC | 4 (33.3) | 8 (66.7) | ||||
ABC/3TC | 5 (20.0) | 20 (80.0) | ||||
D4T base | 1 (8.3) | 11 (91.7) | 0.42b (0.05–3.67) | 0.77 | 0.20 (0.02–1.86) | 0.16 |
DDI base | 0 (0.0) | 8 (100.0) | ||||
Other | 1 (25.0) | 3 (75.0) | 2.67 (0.21–38.56) | 0.44 | 1.59 (0.08–33.3) | 0.77 |
AZT | 9 (11.7) | 68 (88.3) | 1 | |||
CD4 count (cells/mm3) | ||||||
< 200 | 6 (11.1) | 48 (88.9) | 0.68 (0.27–1.73) | 0.43 | 0.59 (0.22–1.57) | 0.29 |
200–350 | 8 (8.3) | 88 (91.7) | 0.50 (0.24–1.07) | 0.07 | 0.56 (0.26–1.19) | 0.13 |
> 350 | 57 (15.2) | 318 (84.8) | 1 | 1 | ||
Parity | ||||||
Multip with PPTD | 3 (75.0) | 1 (25.0) | 15.19 (1.85–125.8) | 0.012 | 13.28 (1.89–93.5) | 0.009 |
Multip without PPTD | 16 (17.4) | 76 (82.6) | 1.64 (0.86–3.04) | 0.12 | 1.56 (0.81–3.01) | 0.18 |
Nulliparous | 52 (12.1) | 377 (87.9) | 1 | 1 | ||
Hepatitis C | ||||||
Positive | 7 (33.3) | 14 (66.7) | 3.20 (1.25–8.19) | 0.015 | 4.66 (1.71–12.75) | 0.003 |
Negative | 64 (12.7) | 440 (87.3) | 1 | 1 | ||
Race | ||||||
Black | 48 (13.3) | 312 (86.7) | 1.01 (0.54–1.87) | 0.40 | 1.49 (0.71–3.15) | 0.29 |
Other | 7 (18.4) | 31 (81.6) | 1.49 (0.59–3.79) | 0.97 | 3.27 (1.16–9.16) | 0.025 |
Caucasian | 16 (12.6) | 111 (87.4) | 1 | 1 |
Combined OR for AZT/3TC, Tdf/3TC, ABC/3TC backbones
Combined OR for d4T- and DDI-based backbones.