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. 2015 Jun 5;18(1):19933. doi: 10.7448/IAS.18.1.19933

Table 2.

Maternal characteristics and risk of pre-term delivery

Predictor variable Pre-term N (%) Term N (%) Unadjusted OR p Adjusted OR p
Total 71 (13.5) 454 (86.5)
Year of delivery
 1988–1996 17 (16.8) 84 (83.2) 1.05 (0.48–1.48) 0.9
 1997–2006 34 (11.6) 259 (88.4) 0.73 (0.38–1.38) 0.33
 2007–2011 20 (15.3) 111 (84.7) 1
Age (years)
  > 35 15 (11.8) 112 (88.2) 0.91 (0.35–1.63) 0.84 0.71 (0.27–1.87) 0.49
 25–35 47 (14.2) 285 (85.8) 1.09 (0.48–1.52) 0.82 0.98 (0.45–2.15) 0.97
  < 25 9 (13.8) 56 (86.2) 1 1
ART treatment
 No treatment 13 (25.0) 39 (75.0) 2.70 (1.20–6.09) 0.017 1.50 (0.33–6.78) 0.60
 NRTI/NNRTI 14 (8.8) 145 (91.2) 0.81 (0.40–1.66) 0.56 0.67 (0.27–1.63) 0.37
 Boosted 23 (19.3) 96 (80.7) 2.01 (1.02–3.97) 0.045 2.17 (1.05–4.51) 0.038
 Unboosted 21 (10.8) 174 (89.2) 1 1
NRTI backbone
 None 13 (25.5) 38 (74.5) 2.59 (1.04–6.42) 0.041 1.40 (0.26–7.59) 0.69
 AZT/3TC 37 (11.5) 285 (88.5) 1.12a (0.53–2.35) 0.44 0.50 (0.18–1.36) 0.17
 Tdf/3TC 4 (33.3) 8 (66.7)
 ABC/3TC 5 (20.0) 20 (80.0)
 D4T base 1 (8.3) 11 (91.7) 0.42b (0.05–3.67) 0.77 0.20 (0.02–1.86) 0.16
 DDI base 0 (0.0) 8 (100.0)
 Other 1 (25.0) 3 (75.0) 2.67 (0.21–38.56) 0.44 1.59 (0.08–33.3) 0.77
 AZT 9 (11.7) 68 (88.3) 1
CD4 count (cells/mm3)
  < 200 6 (11.1) 48 (88.9) 0.68 (0.27–1.73) 0.43 0.59 (0.22–1.57) 0.29
 200–350 8 (8.3) 88 (91.7) 0.50 (0.24–1.07) 0.07 0.56 (0.26–1.19) 0.13
  > 350 57 (15.2) 318 (84.8) 1 1
Parity
 Multip with PPTD 3 (75.0) 1 (25.0) 15.19 (1.85–125.8) 0.012 13.28 (1.89–93.5) 0.009
 Multip without PPTD 16 (17.4) 76 (82.6) 1.64 (0.86–3.04) 0.12 1.56 (0.81–3.01) 0.18
 Nulliparous 52 (12.1) 377 (87.9) 1 1
Hepatitis C
 Positive 7 (33.3) 14 (66.7) 3.20 (1.25–8.19) 0.015 4.66 (1.71–12.75) 0.003
 Negative 64 (12.7) 440 (87.3) 1 1
Race
 Black 48 (13.3) 312 (86.7) 1.01 (0.54–1.87) 0.40 1.49 (0.71–3.15) 0.29
 Other 7 (18.4) 31 (81.6) 1.49 (0.59–3.79) 0.97 3.27 (1.16–9.16) 0.025
 Caucasian 16 (12.6) 111 (87.4) 1 1
a

Combined OR for AZT/3TC, Tdf/3TC, ABC/3TC backbones

b

Combined OR for d4T- and DDI-based backbones.