Table 2.
Changes of serum thyroid hormones level (nmol/L) in WT and MT-I/II KO mice following NI, 10 HI, or 100 HI intake for 14 days.
| Group | T3 | T4 | FT3 | FT4 |
|---|---|---|---|---|
| WT | ||||
| NI | 0.72 ± 0.13 | 26.08 ± 14.21 | 4.80 ± 0.42 | 28.56 ± 4.51 |
| 10 HI | 0.53 ± 0.09 | 33.50 ± 4.45 | 4.26 ± 0.41 | 31.42 ± 0.95 |
| 100 HI | 0.71 ± 0.13 | 34.70 ± 13.24 | 4.61 ± 0.25 | 33.20 ± 4.55 |
| MT-I/II KO | ||||
| NI | 0.58 ± 0.15 | 20.05 ± 4.68 | 4.04 ± 0.77 | 25.69 ± 0.97 |
| 10 HI | 0.69 ± 0.13 | 22.53 ± 7.79 | 4.78 ± 0.05 | 27.22 ± 1.03 |
| 100 HI | 0.80 ± 0.22 | 17.73 ± 6.76 | 5.01 ± 0.73 | 23.99 ± 1.92* |
*In 100 HI group, compared to WT mice, there was a significant difference in serum thyroid hormones level (FT4) in MT-I/II KO mice (P < 0.05). N = 8 for each group.