Table 2.
Antibacterial and cytotoxic effects of the compounds HPE-B11.8 and SPE-B5.4 in comparison with Dragon's blood extracted from medicinal plant D. cochinchinensis Lour.
| Test organisms/cancer cell line | SPE-B11.8 | SPE-B5.4 | Dragon's blood extract |
|---|---|---|---|
| MIC/IC50 (μg/ml) | |||
| MRSE ATCC 35984 | 15.63 ± 1.18 | 0.04 ± 0.00 | 4.88 ± 0.05 |
| MRSA ATCC 25923 | 62.5 ± 2.26 | 0.04 ± 0.00 | 4.88 ± 0.05 |
| E. coli ATCC 25922 | Inactive | 2.24 ± 0.01 | 9.77 ± 0.23 |
| K. pneumoniae ATCC 13883 | 62.5 ± 2.26 | 0.04 ± 0.00 | 4.88 ± 0.05 |
| F. graminearum | Inactive | 9.77 ± 0.23 | 19.53 ± 0.80 |
| Hep G2 | 41.63 ± 0.61 | 0.23 ± 0.05 | 77.91 ± 0.22 |
| MCF-7 | 29.54 ± 2.89 | 0.18 ± 0.05 | 70.00 ± 7.08 |