Fig. 3.

Percent of functional protein categories showing differences in the cell wall between H37Rv and the ΔsecA2 mutant. Shown is the percent of proteins in a given functional category showing SecA2-dependence, defined as ≥twofold difference, p < 0.01 between H37Rv and ΔsecA2 or exclusively identified in one of the two strains (supplemental Tables S4–S7). With the exception of SBPs (44, 55), Mce transporters (representing Mce1–4 systems) (68), and DosR-regulated proteins (58), functional groups were predicted by Tuberculist (47). The total number of proteins in each functional category is denoted in parentheses. # indicates no proteins in that category.