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. 2015 Mar 26;14(6):1501–1516. doi: 10.1074/mcp.M114.044685

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© 2015 by The American Society for Biochemistry and Molecular Biology, Inc.

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Fig. 8. — Relative quantitation of proteins in H37Rv and ΔsecA2 mutant cytoplasmic fractions. A, The 1810 cytoplasmic proteins identified by LC-MS/MS by a minimum of two peptides were assigned to functional categories according to Tuberculist (47). B, Ratios for the 1266 proteins identified by an average ≥4 spectral counts in H37Rv and/or ΔsecA2 are shown plotted by log₂ (ΔsecA2/H37Rv) and −log₁₀(p value). The shaded area of the graph indicates proteins showing twofold differences, p < 0.01. DosR-regulated proteins (red triangles) and PknG (black circle) are marked on the plot.