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Rescue of ΔF508-CFTR in cells treated with VX-809 and FGFR inhibitors. 293-GT cells stably expressing ΔF508-CFTR were treated with the indicated concentrations of VX-809 plus SU5402 or AZD4547 and analyzed for rescue of ΔF508-CFTR using the halide-exchange (Cellomics) assaay. Data are mean ± S.E., n = three independent experiments, each performed in triplicates, three fields per well (70–300 cells per field).
