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. 2015 Mar 29;14(6):1569–1583. doi: 10.1074/mcp.M114.046375

Table I. Results of the esiRNA screen. The top 20 hit genes that displayed a difference in average fluorescence intensity ΔFIavg (between FIG-stimulated sample and nonsilencing control) of at least 9%.

Gene name Protein name Accession No. Rescue (%)
RIPK4 Receptor-interacting serine/threonine-protein kinase 4 P57078 22
SHPK Sedoheptulokinase Q9UHJ6 20
MAP3K13 Mitogen-activated protein kinase kinase kinase 13 O43283 19
FGFR1 Fibroblast growth factor receptor 1 P11362 16
CDK10 Cyclin-dependent kinase 10 Q15131 16
RPS6KC1 Ribosomal protein S6 kinase delta-1 Q96S38 16
PANK4 Pantothenate kinase 4 Q9NVE7 14
DTYMK Thymidylate kinase P23919 14
ERN1 Serine/threonine-protein kinase/endoribonuclease IRE1 O75460 14
BRAF Serine/threonine-protein kinase B-raf P15056 13
DUSP22 Dual specificity protein phosphatase 22 Q9NRW4 13
IPMK Inositol polyphosphate multikinase Q8NFU5 13
PCK2 Phosphoenolpyruvate carboxylase Q16822 13
CLK3 Dual specificity protein kinase CLK3 P49761 13
MET Tyrosine-protein kinase Met P08581 12
CAMK2B Calcium/calmodulin-dependent protein kinase type II subunit beta Q13554 12
SOCS1 Suppressor of cytokine signaling 1 O15524 11
NEK10 Serine/threonine-protein kinase Nek10 Q6ZWH5 11
PRKAR2B cAMP-dependent protein kinase type II-beta regulatory subunit P31323 9
PANK1 Pantothenate kinase 1 Q8TE04 9