Table 6. Estimated Number of Nigral Pigmented Neuronal Populations and Volumetric Measurements with Corresponding Values of Gunderson's Coefficient Errors in the Dys and C Groups. The table shows single values obtained in each Dys and C subject in terms of estimated number of pigmented nigral neurons counted. Each mean neuronal counting estimation has a corresponding mean cell body, nuclear, and nucleolar volume for all examined subjects. CE is an indicator of precision for the performed estimations and is generally acceptable if <0.10.
Subject# | Mean Pigmented Neuronal Count | CE | Mean Cellular Volume | CE | Mean Nuclear Volume | CE | Mean Nucleolar Volume | CE |
1 (Dys) | 530,990.7 | 0.05 | 18,457.9 | 0.006 | 2,332.3 | 0.006 | 38.1 | 0.007 |
2 (Dys) | 409,690.0 | 0.07 | 12,777.6 | 0.003 | 1,884.7 | 0.003 | 31.0 | 0.004 |
3 (Dys) | 494,021.3 | 0.06 | 10,641.4 | 0.005 | 1,097.5 | 0.006 | 17.2 | 0.022 |
4 (Dys) | 604,631.9 | 0.06 | 12,589.7 | 0.004 | 1,730.0 | 0.005 | 27.3 | 0.005 |
5 (Dys) | 682,198.8 | 0.05 | 21,377.8 | 0.005 | 1,752.9 | 0.005 | 24.4 | 0.006 |
6 (Dys) | 491,138.2 | 0.05 | 17,297.2 | 0.007 | 1,510.4 | 0.007 | 24.8 | 0.006 |
7 (Dys) | 275,364.9 | 0.08 | 16,926.6 | 0.009 | 1,840.5 | 0.009 | 21.6 | 0.011 |
8 (Dys) | 322,533.2 | 0.07 | 17,586.4 | 0.007 | 2,002.1 | 0.007 | 23.7 | 0.062 |
9 (Dys) | 405,516.6 | 0.06 | 5,273.8 | 0.006 | 581.8 | 0.009 | 8.0 | 0.008 |
10 (Dys) | 696,735.9 | 0.05 | 13,886.4 | 0.004 | 2,286.8 | 0.005 | 21.3 | 0.049 |
11 (Dys) | 518,118.1 | 0.06 | 16,352.0 | 0.006 | 2,328.5 | 0.007 | 37.4 | 0.007 |
12 (Dys) | 414,003.9 | 0.06 | 17,771.6 | 0.006 | 1,533.1 | 0.006 | 30.6 | 0.079 |
13 (Dys) | 610,877.4 | 0.05 | 15,829.5 | 0.005 | 2,100.2 | 0.005 | 32.0 | 0.005 |
14 (C) | 787,705.8 | 0.06 | 13,858.9 | 0.004 | 1,115.2 | 0.005 | 22.0 | 0.016 |
15 (C) | 648,925.7 | 0.06 | 11,253.3 | 0.007 | 1,390.6 | 0.008 | 23.6 | 0.045 |
16 (C) | 351,255.9 | 0.05 | 15,631.9 | 0.003 | 1,663.0 | 0.003 | 25.8 | 0.004 |
17 (C) | 856,559.1 | 0.06 | 11,864.0 | 0.003 | 1,600.5 | 0.003 | 24.0 | 0.004 |
18 (C) | 621,172.8 | 0.07 | 15,532.5 | 0.007 | 2,084.9 | 0.008 | 29.0 | 0.053 |
19 (C) | 370,591.1 | 0.06 | 20,711.7 | 0.010 | 1,585.1 | 0.009 | 21.1 | 0.010 |
20 (C) | 571,960.5 | 0.06 | 18,168.9 | 0.003 | 1,704.5 | 0.004 | 27.3 | 0.048 |
21 (C) | 696,553.0 | 0.06 | 15,519.3 | 0.003 | 1,365.8 | 0.003 | 26.8 | 0.034 |
22 (C) | 488,401.4 | 0.05 | 14,754.4 | 0.004 | 1,327.2 | 0.005 | 25.1 | 0.057 |
23 (C) | 800,241.8 | 0.05 | 18,947.8 | 0.004 | 1,660.0 | 0.004 | 28.4 | 0.004 |
24 (C) | 718,722.8 | 0.04 | 15,375.8 | 0.004 | 2,007.7 | 0.003 | 29.7 | 0.004 |
25 (C) | 750,282.5 | 0.05 | 16,342.6 | 0.004 | 1,788.9 | 0.005 | 23.0 | 0.059 |
26 (C) | 773,662.1 | 0.05 | 15,258.7 | 0.003 | 2,315.1 | 0.003 | 30.5 | 0.004 |
Abbreviations: C, Control; CE, Coefficient of Error (of Gunderson); Dys, Dystonia.