Table 1.

Participant Demographics

	UC a N=9	All HIV N=20	Controls N=12	p value
Sex
Male, number (%)	7 (77.8)	19 (95)	10 (83.3)	0.36
Female, number	2 (22.2)	1 (5)	2 (16.7)
Age, years
Mean±SDb	39.3±14	45.4±10.3	42.5±12.1	0.29
Race
White, number (%)	9 (100)	15 (75)	6 (50)	0.15
Nonwhite, number	0 (0)	5 (25)	6 (50)
Histology scorec
Number with normal to mild (%)	0 (0)	19 (95)	12 (100)	<0.001 (UC vs. HIV)
Number with moderate to severe (%)	9 (100)	1 (5)	0 (0)	<0.001 (UC vs. controls)
				1.0 (HIV vs. controls)

HIV-infected participantsd
Characteristic	HIVDVL N=10	HIVNDVL N=10	p value
Plasma viral load
Mean log10 copies±SD	4.4±0.5	n/a	n/a
CD4+ T-lymphocyte count
Mean cells/μl±SD	301.6±232.3	692.4±351.7	<0.001
ARTe at the time of biopsy
Yes, number (%)	6 (60)	9 (90)	0.30
No	4 (40)	1 (10)
Number of years from HIV diagnosisf	n=6	n=7
Mean±SD	17.5±5.2	10.1±3.3	0.01
Histology score
Normal, number (%)	5 (50)	10 (100)	0.03
Mild	4 (40)	0 (0)
Moderate	0 (0)	0 (0)
Severe	1 (10)	0 (0)

^aUlcerative colitis.

^bStandard deviation.

^cNormal histology score=grade 1, mild histology score=grade 2–3, moderate histology score=grade 4, severe histology score=grade 5–6.

^dHIV-infected subjects were dichotomized according to detectable plasma viral load (HIV^DVL) or nondetectable (<50 copies/ml) (HIV^NDVL) plasma viral load.

^eAntiretroviral therapy.

^fTime from diagnosis was not available for all participants.