Table 1.
Socio-demographic profile, clinical variables, sense of coherence, anxiety and depression symptoms and health-related quality of life in inflammatory bowel disease patients and comparisons between Crohn’s disease and ulcerative colitis n (%)
| Total (n =147) | CD (n = 64) | UC (n = 83) | CD vs UC (P value) | |
| Demographic | ||||
| Sex | 0.8851 | |||
| Male | 63 (42.9) | 27 (42.2) | 36 (43.4) | |
| Female | 84 (57.1) | 37 (57.8) | 47 (56.6) | |
| Race | 0.2181 | |||
| Latin/Mixed-race | 96 (65.3) | 44 (68.8) | 52 (62.7) | |
| White | 36 (24.5) | 16 (25.0) | 20 (24.1) | |
| Black | 9 (6.1) | 3 (4.7) | 6 (7.2) | |
| Asian | 5 (3.4) | 0 (0) | 5 (6.0) | |
| Indian | 1 (0.7) | 1 (1.6) | 0 (0) | |
| Age | 45.1 ± 14.1 | 43.9 ± 14.9 | 46.1 ± 13.9 | 0.3502 |
| Years of education | 8.4 ± 4.9 | 8.1 ± 4.9 | 8.5 ± 5.1 | 0.6272 |
| Marital status | ||||
| With spouse/partner | 98 (66.7) | 46 (71.9) | 52 (62.7) | 0.2391 |
| Gross monthly Income (USD) | 482.9 ± 560.0 | 487.6 ± 665.2 | 479.3 ± 467.4 | 0.9302 |
| Clinical | ||||
| Time since diagnosis (mo) | 80.5 ± 71.8 | 79.7 ± 73.9 | 81.0 ± 70.6 | 0.9142 |
| Relapse rate | 0.0231 | |||
| Low (0-2 in 2 yr) | 53 (36.3) | 23 (36.5) | 30 (36.1) | |
| Moderate (3-5 in 2 yr) | 61 (41.8) | 20 (31.7) | 41 (49.4) | |
| High (≥ 6 in 2 yr) | 32 (21.9) | 20 (31.7) | 12 (14.5) | |
| Surgery for IBD | 26 (17.7) | 20 (31.3) | 6 (7.2) | < 0.0011 |
| CDAI, mean ± SD | NA | 64.75 ± 43.57 | NA | |
| TWT, mean ± SD | NA | NA | 7.53 ± 1.61 | |
| Disease in remission | 90 (61.2) | 62 (96.9) | 28 (33.7) | < 0.0011 |
| Psychological | ||||
| SOC | 138.4 ± 24.8 | 138.6 ± 23.2 | 138.2 ± 26.1 | 0.9232 |
| Anxiety symptoms (HADS-A) | 5.58 ± 4.30 | 6.00 ± 4.06 | 5.26 ± 4.47 | 0.3022 |
| Depressive symptoms (HADS-D) | 5.27 ± 3.78 | 5.00 ± 3.83 | 5.48 ± 3.74 | 0.4452 |
| HADS-A ≥ 8 (anxiety) | 37 (25.2) | 21 (32.8) | 16 (19.3) | 0.0611 |
| HADS-D ≥ 8 (depression) | 36 (24.5) | 15 (23.4) | 21 (25.3) | 0.7941 |
| HRQoL | ||||
| Overall HRQoL | 3.88 ± 0.81 | 3.94 ± 0.75 | 3.84 ± 0.85 | 0.4852 |
| Satisfaction with Health | 3.59 ± 0.96 | 3.34 ± 1.10 | 3.78 ± 0.80 | 0.0082 |
| Physical HRQoL | 3.48 ± 0.64 | 3.42 ± 0.60 | 3.54 ± 0.67 | 0.2722 |
| Mental HRQoL | 3.82 ± 0.67 | 3.68 ± 0.61 | 3.92 ± 0.71 | 0.0302 |
| Social Relations HRQoL | 3.90 ± 0.74 | 3.98 ± 0.74 | 3.83 ± 0.74 | 0.2342 |
| Environment HRQoL | 3.38 ± 0.53 | 3.41 ± 0.54 | 3.36 ± 0.53 | 0.5542 |
Data are presented as mean ± SD for continuous variables and as n (%) for categorical variables; remission was defined according to CDAI (< 150) and TWT (≤ 6) scores, accordingly;
1
χ2 test;
2
Two-tailed t-test. NA: Not applicable; CDAI: Crohn's disease activity index; TWT: Truelove-Witts ulcerative colitis severity index; HRQoL: Health-related quality of life; SOC: Sense of coherence; UC: Ulcerative Colitis; CD: Crohn’s disease.