Table 2.
Univariable associations of demographic, clinical and psychological variables with anxiety, depression and health-related quality of life (n =147)
| Anxiety symptoms | Depressive symptoms | Overall HRQoL | Satisfaction with Health | Physical HRQoL | Mental HRQoL | Social Relations HRQoL | Environment HRQoL | |
| Sex1 | ||||||||
| Male | 5.01 ± 4.17 | 4.40 ± 3.2a | 4.02 ± 0.66 | 3.65 ± 0.99 | 3.65 ± 0.59b | 3.93 ± 0.47 | 3.96 ± 0.71 | 3.40 ± 0.54 |
| Female | 6.01 ± 4.37 | 5.93 ± 4.0 | 3.79 ± 0.89 | 3.55 ± 0.95 | 3.36 ± 0.65 | 3.73 ± 0.78 | 3.85 ± 0.77 | 3.36 ± 0.53 |
| Race2 | ||||||||
| Latin/Mixed-race | 5.40 ± 4.00 | 5.02 ± 3.62 | 3.95 ± 0.81 | 3.63 ± 0.93 | 3.50 ± 0.62 | 3.84 ± 0.67 | 3.92 ± 0.73 | 3.39 ± 0.55 |
| White | 5.80 ± 4.35 | 5.86 ± 3.98 | 3.66 ± 0.72 | 3.43 ± 1.01 | 3.47 ± 0.65 | 3.77 ± 0.72 | 3.70 ± 0.83 | 3.39 ± 0.48 |
| Other | 6.19 ± 5.91 | 5.50 ± 4.35 | 4.00 ± 0.89 | 3.75 ± 1.06 | 3.39 ± 0.77 | 3.75 ± 0.60 | 4.17 ± 0.58 | 3.29 ± 0.54 |
| Age3 | 0.125 | 0.188a | -0.181a | 0.081 | -0.196a | -0.036 | -0.244d | -0.078 |
| Education (yr)3 | 0.016 | -0.156 | 0.166a | 0.006 | 0.132 | 0.038 | 0.166a | 0.212a |
| Marital status1 | ||||||||
| Living alone | 5.40 ± 4.52 | 5.39 ± 4.30 | 3.86 ± 0.89 | 3.45 ± 0.96 | 3.47 ± 0.70 | 3.85 ± 0.82 | 3.87 ± 0.70 | 3.35 ± 0.59 |
| Living with spouse | 5.67 ± 4.21 | 5.21 ± 3.51 | 3.90 ± 0.77 | 3.66 ± 0.96 | 3.49 ± 0.62 | 3.80 ± 0.59 | 3.91 ± 0.77 | 3.39 ± 0.50 |
| Income3 | -0.022 | -0.123 | 0.045 | -0.060 | 0.107 | 0.087 | 0.116 | 0.252b |
| Disease1 | ||||||||
| CD | 6.00 ± 4.06 | 5.00 ± 3.83 | 3.94 ± 0.75 | 3.34 ± 1.10b | 3.42 ± 0.60 | 3.68 ± 0.61a | 3.98 ± 0.74 | 3.41 ± 0.54 |
| UC | 5.26 ± 4.47 | 5.48 ± 3.74 | 3.84 ± 0.85 | 3.78 ± 0.80 | 3.54 ± 0.67 | 3.92 ± 0.71 | 3.83 ± 0.74 | 3.36 ± 0.53 |
| Time since diagnosis3 | 0.274d | 0.259b | -0.1116 | -0.097 | -0.177a | -0.217b | -0.202a | 0.019 |
| Surgery for IBD1 | ||||||||
| No | 5.56 ± 4.38 | 5.50 ± 3.73 | 3.84 ± 0.82 | 3.59 ± 0.97 | 3.48 ± 0.63 | 3.82 ± 0.66 | 3.87 ± 0.73 | 3.34 ± 0.52 |
| Yes | 5.69 ± 4.00 | 4.23 ± 3.88 | 4.08 ± 0.74 | 3.62 ± 0.94 | 3.50 ± 0.70 | 3.81 ± 0.73 | 4.03 ± 0.80 | 3.56 ± 0.58 |
| Relapse rate4 | 0.141 | 0.057 | -0.040 | -0.077 | -0.228b | -0.136 | 0.009 | -0.212a |
| Disease activity1 | ||||||||
| In Remission | 5.71 ± 4.60 | 5.13 ± 3.97 | 3.90 ± 0.81 | 3.52 ± 1.03 | 3.50 ± 0.62 | 3.77 ± 0.63 | 3.95 ± 0.78 | 3.43 ± 0.57 |
| Active | 5.39 ± 3.81 | 5.49 ± 3.48 | 3.86 ± 0.81 | 3.70 ± 0.84 | 3.47 ± 0.68 | 3.89 ± 0.74 | 3.81 ± 0.69 | 3.29 ± 0.47 |
| SOC5 | -0.398d | -0.458d | 0.271d | 0.232b | 0.313d | 0.341d | 0.266b | 0.266b |
| Anxiety symptoms3 | N/A | 0.551d | -0.424d | -0.431d | -0.567d | -0.503d | -0.500d | -0.341d |
| Depressive symptoms3 | 0.551d | N/A | -0.327d | -0.272d | -0.463d | -0.473d | -0.459d | -0.375d |
1
Two-tailed t-test;
2
One-way ANOVA;
3
Pearson correlation coefficient;
4
Spearman correlation coefficient);
5
Sense of Coherence.
d
P < 0.01,
b
P < 0.01,
a
P < 0.05 vs control. IBD: Inflammatory bowel disease; CD: Crohn's disease; UC: Ulcerative colitis; NA: Not applicable; HRQoL: Health-related quality of life.