Binding of CLL mAbs to oxidation-induced molecular adducts and advanced oxidation protein products. CLL mAbs were used as primary Ab for the colorimetric ELISA. Samples were grouped on the basis of BCR stereotypy. The bars represent the mean OD value as measured for CLL mAbs assigned to each of stereotyped subsets #1, #2, or #8. The mAbs tested, as well as the mean OD values of 3 replicates per sample are listed in supplemental Table 5. All determinations were performed in triplicate. *P < .05, **P < .005. AOPP-HSA, human serum albumin conjugated to advanced oxidation protein products; HNE-BSA, BSA modified with 4-hydroxynonenal.