Table 2.

Asymptomatic cases of proven or probable histoplasmosis (incidental radiological findings)

	Age (gender)	Probable location of infection	Visited bat habitat	Radiology	Travel partner with histoplasmosis*	Time lag (mo)†	Serology	Additional diagnostic tests
15	29 (M)	Central America m/p Guatemala	Yes	ND	Yes (#1)	16	Positive	—
16	31 (M)	m/p Mexico	Yes	3 Nodules of which 2 calcified	No	108	Negative‡	—
17	30 (F)	Guatemala	Yes	Multiple calcified nodules/masses	Yes (#18)	96	Negative§	—
18	32 (M)	Guatemala	Yes	2 Nodules, 1 calcified	Yes (#17)	96	Negative§	—
19	37 (M)	Central America m/p Guatemala	Yes	2 Partially calcified nodules	No	36	Positive	—
20	66 (M)	South or Central America	No	RLL mass	No	18	Borderline∥	Excisional biopsy
21	33 (M)	Central America	No	Multiple calcified foci—lung and spleen	No	120	ND	—
22	54 (M)	Indianapolis, IN	No	Multiple calcified nodules	No	36	ND	—
23	52 (M)	Dominican Republic	Yes	Calcified nodule	No	72	ND	—

F = female; M = male; m/p = most probably; ND = not done or uninterpretable; RLL = right lower lobe.

^*Proven or probable.

^†From return from endemic area until presentation.

^‡Diagnosis (probable) based on typical radiological appearance.

^§Diagnosis based on radiological appearance and travel partner with proven or probable histoplasmosis.

^∥Diagnosis based on histopathology of mass: necrotizing granulomata, yeasts with morphology of Histoplasma capsulatum in adjacent lymph node.