Table 2.
Age (gender) | Probable location of infection | Visited bat habitat | Radiology | Travel partner with histoplasmosis* | Time lag (mo)† | Serology | Additional diagnostic tests | |
---|---|---|---|---|---|---|---|---|
15 | 29 (M) | Central America m/p Guatemala | Yes | ND | Yes (#1) | 16 | Positive | — |
16 | 31 (M) | m/p Mexico | Yes | 3 Nodules of which 2 calcified | No | 108 | Negative‡ | — |
17 | 30 (F) | Guatemala | Yes | Multiple calcified nodules/masses | Yes (#18) | 96 | Negative§ | — |
18 | 32 (M) | Guatemala | Yes | 2 Nodules, 1 calcified | Yes (#17) | 96 | Negative§ | — |
19 | 37 (M) | Central America m/p Guatemala | Yes | 2 Partially calcified nodules | No | 36 | Positive | — |
20 | 66 (M) | South or Central America | No | RLL mass | No | 18 | Borderline∥ | Excisional biopsy |
21 | 33 (M) | Central America | No | Multiple calcified foci—lung and spleen | No | 120 | ND | — |
22 | 54 (M) | Indianapolis, IN | No | Multiple calcified nodules | No | 36 | ND | — |
23 | 52 (M) | Dominican Republic | Yes | Calcified nodule | No | 72 | ND | — |
F = female; M = male; m/p = most probably; ND = not done or uninterpretable; RLL = right lower lobe.
Proven or probable.
From return from endemic area until presentation.
Diagnosis (probable) based on typical radiological appearance.
Diagnosis based on radiological appearance and travel partner with proven or probable histoplasmosis.
Diagnosis based on histopathology of mass: necrotizing granulomata, yeasts with morphology of Histoplasma capsulatum in adjacent lymph node.