Table 2.

Statistical comparisons of parasitological and molecular parameters of mice inoculated with strains of Trypanosoma cruzi I, II, and IV treated with benznidazole (TBZ), 100 mg/kg/day-20×, and untreated controls (NT)

Parameter*	Total		TcI		TcII		TcIV
	NT × TBZ	P	NT × TBZ	P	NT × TBZ	P	NT × TBZ	P
PP (in days)	6.3 × 0.3	< 0.001	PA	−	15.6 × 0.5	0.021	3.3 × 0.3	< 0.001
Pmax† (×103)	21.7 × 0.35	0.009	PA	−	55.72 × 0.37	0.021	5.42 × 0.35	0.021
DPmax‡	7.6 × 1.2	0.003	PA	−	15.3 × 5.5	0.021	7.5 × 2.0	< 0.001
%+FBE§	55.2 × 0.0	< 0.001	PA	−	83.3 × 0.0	0.021	70.0 × 0.0	< 0.001
%+HC¶	68.9 × 36.4	< 0.001	73.2 × 40.0	0.002	100.0 × 37.0	< 0.001	50.9 × 33.3	NS
%+cPCR∥	45.0 × 35.6	NS	14.0 × 12.0	NS	77.1 × 29.7	< 0.001	17.0 × 23.0	NS
%MOR**	6.7 × 5.6	NS	6.0 × 2.0	NS	2.0 × 1.0	NS	7.0 × 6.0	NS
No. of significant differences	5/7		1/3		6/7		4/7

^*The Student's t test was used in comparisons of PP, Pmax and Dpmax, and the χ² for the other parameters.

^†Number of trypomastigotes/0.1 mL of blood at the peak of parasitemia.

^‡Day of peak parasitemia.

^§Percentage of mice with positive fresh blood examination.

^¶Percentage of mice with positive blood culture.

^∥Percentage of mice with positive conventional polymerase chain reaction.

^**Cumulative mortality rate.

PP = mean patent period; PA = parasitemia absent; NS = not significant.