Table 2.
Sensitivities and specificities of each test by zone
| Zone* | Number of schools | Test method | Sensitivity (95% CI) | Specificity (95% CI) |
|---|---|---|---|---|
| A | 9 (N = 304) | CCA-1 | 90.4 (83.2, 95.9) | 49.1 (41.1, 57.2) |
| CCA-2 | 74.2 (61.5, 86.1) | 86.2 (79.9, 91.6) | ||
| Multiple Kato-Katz | 96.9 (88.9, 99.9) | 83.2 (71.3, 96.1) | ||
| SWAP ELISA | 67.5 (57.1, 78.1) | 73.7 (66.0, 80.7) | ||
| B | 12 (N = 409) | CCA-1 | 95.1 (88.8, 98.6) | 46.6 (40.6, 52.9) |
| CCA-2 | 77.1 (64.1, 88.8) | 85.3 (80.4, 89.9) | ||
| Multiple Kato-Katz | 91.1 (76.1, 99.5) | 91.1 (85.7, 96.1) | ||
| SWAP ELISA | 61.3 (47.7, 76.0) | 87.0 (82.6, 91.0) | ||
| C | 28 (N = 989) | CCA-1 | 78.0 (63.6, 88.2) | 65.1 (61.9, 68.3) |
| CCA-2 | 88.1 (77.6, 94.6) | 92.3 (90.3, 94.1) | ||
| Multiple Kato-Katz | 94.0 (80.8, 99.8) | 96.7 (94.7, 98.9) | ||
| SWAP ELISA | 61.7 (49.2, 74.0) | 87.7 (85.3, 89.9) |
CCA = circulating cathodic antigen; CI = confidence interval; SWAP ELISA = soluble adult worm antigen preparation enzyme-linked immunosorbent assay.
*
Zone A includes schools within 1,200 m of the lake; Zone B includes schools located between 1,200 and 3,800 m of the lake; and Zone C includes schools further than 3,800 m from the lake.