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. 2015 May 28;6:7203. doi: 10.1038/ncomms8203

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(a) Graph depicting the number and proportion of all and shared (common) RUNX1-ETO targets among differentially expressed genes (DEGs) in the different cell populations. (b) Venn diagram showing only a small overlap between the downregulated (top) and upregulated (bottom) transcripts from RUNX1-ETO-target genes in the HE and in cultured myeloid progenitors after RUNX1-ETO induction. (c) Analysis of the influence of RUNX1-ETO binding on the kinetics of upregulation and downregulation of genes during the EHT. The heat map shows an unbiased clustering of the fold change in gene expression during the EHT with and without RUNX1-ETO induction with the different clusters (00, 01, 02 and so on) indicated on the right. Right panel: predominant gene ontology terms of genes belonging to the different clusters.