Figure 6.
Concentration–response curves for sodium nitroprusside in the absence or presence of (A) kaempferol or (B) large-conductance calcium-activated potassium channel inhibitor with or without kaempferol. Rings from porcine coronary arteries were incubated with kaempferol (3 × 10−6 M), iberiotoxin (10−7 M) together with kaempferol (3 × 10−6 M) or the vehicle control (ethanol, 0.1%) for 30 min. Rings were then contracted with U46619 (3 × 10−8 M) before sodium nitroprusside was added cumulatively. n = 5–6. *P < 0.05, significantly different from the control group.